Category: streetinsider

Kiran Biotech is developing AvidinOX®, a protein-based platform designed to improve site-specific localization of biotinylated compounds. The technology enables covalent anchoring at targeted sites, supporting precision research in molecular imaging, diagnostics, and tissue engineering.

Italy, 1st Jul 2025, Grand Newswire – The Italian biotech startup is exploring a new approach to molecular localization based on covalent anchoring of biotin-tagged compounds.

Kiran Biotech, an Italian research-based company operating in the field of molecular delivery technologies, is developing a novel platform aimed at improving the localization of biotinylated compounds through a proprietary protein-based anchoring mechanism called AvidinOX®.

The platform is designed to explore new ways of enhancing the site-specific retention of molecules, with the goal of improving selectivity and reducing unwanted dispersion in preclinical research and diagnostic settings.

AvidinOX® is a chemically modified avidin derivative that forms stable covalent interactions with tissue proteins at the site of application.

Once anchored, the treated site can selectively bind biotinylated agents delivered systemically.

This concept supports the investigation of modular delivery strategies, where localization and compound activity are decoupled.

Kiran biotech is studying the potential use of this approach in different research domains, including molecular imaging, tissue engineering, and site-preparation for systemically delivered probes or cells.

Initial results from preclinical studies and early-stage research programs suggest promising opportunities for further development.

AvidinOX® has been the subject of publications in peer-reviewed journals, including Oncotarget, Oncology Letters, and Bioorganic & Medicinal Chemistry Letters, where its anchoring behavior and molecular compatibility were explored under experimental conditions.

According to Kiran Biotech’s team, the modularity of AvidinOX® may allow future integration with a range of compatible technologies, including biotin-labeled molecules or probes developed by third-party research groups or pharmaceutical companies.

Its anchoring mechanism, once validated and scaled, could serve as a platform to support localized strategies in various investigational frameworks.

Kiran biotech holds a portfolio of intellectual property protecting the AvidinOX® molecule, its production process, and a broad range of research applications involving localization, targeting, and detection.

The company was recently recognized as one of Italy’s emerging innovators in the biotech sector, and it has received support under Italy’s national innovation funding programs.

The company is currently focused on advancing its R&D pipeline, establishing production scale-up protocols under controlled conditions, and initiating collaborative studies with institutions and private partners.

“We see AvidinOX® as an enabling technology.” says Rita De Santis, CEO of Kiran Biotech.

“Our goal is to provide researchers with tools to better explore localization and selective delivery in a wide range of experimental applications.” 

About Kiran Biotech
Kiran Biotech is a privately held Italian company focused on the development of protein-based tools and delivery platforms for use in preclinical research, diagnostics, and biotechnological innovation.

Its mission is to contribute to the evolution of precision strategies through site-specific anchoring technologies.

Media Contact

Organization: IMISEST

Contact Person: Stefano Manzotti

Website: https://imisest.com

Email:
amministrazione@imisest.com

Country:Italy

Release id:30091

Dubai, UAE, 30th June 2025, ZEX PR WIRE, NodeOps Network is thrilled to announce the successful completion of its exclusive Token Generation Event (TGE) on Binance Wallet, where $NODE tokens sold out within minutes of launch. The event, held on June 30 between 08:00 and 10:00 UTC, marked a major milestone for the project and showcased overwhelming demand from the global crypto community.

Hosted as the 27th TGE on Binance Wallet, this launch also marked a strategic first: participation was gated exclusively through Binance Alpha Points, a move that increased user engagement and rewarded Binance’s most active ecosystem participants with early access to NodeOps Network’ decentralized Compute coordination layer. In addition to Binance Wallet, $NODE is accessible on PancakeSwap, supporting broader participation while staying true to the principles of decentralization.

Following the oversubscription, $NODE officially launched for trading at 10:00 AM UTC on a curated set of top global exchanges, including KuCoin, OKX Wallet, Bitget, MEXC, HTX (formerly Huobi), BitMart, LBank, and BingX. This coordinated multi-exchange debut marks a pivotal moment in NodeOps Network’ journey to make decentralized Compute infrastructure accessible at scale, signaling the beginning of what the community is calling “DePIN 2.0”

NodeOps Network: Powering the Future of Decentralized Compute

NodeOps Network is a decentralized infrastructure coordination layer powering the next era of verifiable compute. Designed for scale, the protocol currently orchestrates over 61,000 active nodes, powers 60+ protocols, and has generated $3.8 million in revenue to date with $150M of assets under management. 

Built on top of NodeOps Network, the NodeOps Platform offers a modular product suite—including a no-code Node Console, decentralized Compute Cloud, Staking Hub, Security Hub, and AI Agent Terminal designed to simplify infrastructure deployment across Web3 and AI. The platform addresses the growing complexity of operating compute and node infrastructure in a multi-chain world, supporting networks across BNB Chain, Ethereum, and emerging Layer 2 solutions.

Redefining Token Launches Through Strategic Access

Token Generation Events serve as critical inflection points in the lifecycle of emerging crypto projects, offering early supporters access to native tokens before widespread distribution. With a proven track record of spotlighting successful Web3 projects, Binance continues to play a pivotal role in bridging high-potential protocols with its global user base.

The introduction of Alpha Points as the sole access mechanism to the NodeOps Network TGE signals a clear shift in launch strategy. Traditionally earned through platform engagement, Alpha Points now serve as high-utility assets rewarding loyal, active users with exclusive opportunities to participate in Binance-curated launches.

Tokenomics for Sustainability

$NODE’s tokenomics emphasize stability, real usage, and economic alignment. With a total genesis supply of 678,833,730 tokens, the distribution model incorporates long-term vesting, protocol-based emissions, and a burn-and-mint equilibrium that ties token creation to on-chain revenue. This structure promotes a responsible token economy, ensuring that supply growth is directly tied to value creation, not speculative emissions.

In line with NodeOps’ commitment to transparency and user-centricity, it released a first-of-its-kind interactive tokenomics portal to help users model and better understand the dynamic nature of $NODE’s tokenomics. Its emissions follow a dynamic mint-and-burn model tied to real network usage, anchoring long-term value to platform demand.

Token Allocation Highlights:

• Community & Ecosystem: 47.5%
• Early Backers: 22.5%
• Protocol Incentives: 15%
• Initial Contributors: 15%

NodeOps is positioning itself as the leading DePIN infrastructure platform, uniting tokenized incentives, AI automation, and decentralized compute into a single interface for the future of verifiable systems.

About NodeOps Network

NodeOps Network is an AI-powered, decentralized Compute coordination layer that automates validator and node operations across blockchain networks. Supporting over 60 protocols and 61,000 nodes, NodeOps delivers scalable infrastructure tooling and staking solutions that power the next generation of decentralized applications.

For more information, please visit https://nodeops.network/ 

Singapore, 30th June 2025, ZEX PR WIRE, Zilliqa, the pioneering high performance Layer 1 blockchain platform known for bringing sharding into production, today announced the official transition from Zilliqa 1.0 to Zilliqa 2.0 — a major protocol upgrade that redefines the platform’s capabilities for developers, enterprises, and institutions alike.

As the industry matures, so do its requirements. With Zilliqa 1.0, the world witnessed that high-throughput, sharded blockchains could operate at scale. But in today’s rapidly evolving web3 world, the need for regulatory alignment, composability, and developer-first tooling is greater than ever. Zilliqa 2.0 addresses this with a re-architected, modular platform designed to support verifiable smart contracts, tokenized assets, and next-generation dApps. It represents a complete architectural overhaul, built to meet the demands of today’s blockchain landscape — from EVM compatibility and modular design to regulatory-ready infrastructure that enables  tokenized real-world assets and compliance-driven DeFi.

“Zilliqa 2.0 is more than an upgrade — it’s a transformation. We’re building the blockchain institutions can trust without compromising on the speed, flexibility, or openness that brought us here in the first place. The next era of blockchain won’t be built on hype. It’ll be built on trust, transparency, and technical excellence. That’s what Zilliqa 2.0 stands for”, said Alexander Zahnd, interim CEO of Zilliqa.

Key Upgrades in Zilliqa 2.0

Zilliqa 2.0 launches with full EVM  support, enabling seamless deployment of Ethereum-native applications and tooling. The platform’s modular design future proofs the chain for upgrades, scale, and protocol evolution.At its core are six foundational pillars: a modern Proof-of-Stake consensus, customizable x-shards, seamless cross-chain communication, light client support, and sustainable tokenomics. Looking ahead, Zilliqa’s roadmap includes smart accounts that will bring enhanced on-chain programmability, as well as zero-knowledge (ZK) features to enable privacy-preserving compliance tools like selective disclosure and verifiable credentials. Together, these upgrades deliver a blockchain that’s faster, greener, easier to build on, and ready for real-world adoption at scale. 

This upgrade transforms Zilliqa into a blockchain that’s as attractive to institutions as it is to developers. Whether it’s fintechs launching programmable assets or compliance-driven DAOs building advanced tooling, Zilliqa 2.0 offers a production-ready base layer that bridges real-world needs with decentralized innovation.

“Zilliqa is now institution-ready and developer-friendly,” Zahnd added. “We’ve rebuilt the core to make sure we’re not just fast — we’re also open, composable and built for real-world impact.”

Continuous Commitment to Performance

With over 50 million transactions processed and one of the most proven sharding implementations in production, Zilliqa’s core performance is only accelerating. Validators remain integral to the protocol, and staking continues to offer attractive rewards as the network enters its next chapter.

With Zilliqa 2.0’s debut, staking receives a performance boost:, streamlined validator onboarding, and potential early high APR for users who migrate staking early from Zilliqa 1.0 to Zilliqa 2.0. This dynamic staking model is designed to incentivize early adopters while scaling sustainably as liquidity gradually transitions from the old to the new system.

Over a six-month Aventurine phase, 21 external validators tested the proto-mainnet, generating over 7.5 million blocks and completing 15 successful client upgrades. Now live on mainnet, Zilliqa 2.0 is powering projects building across tokenized assets, (regulated) DeFi, digital identity, fintech infrastructure, and more. Strategic integrations – such as partnerships with LTIN and deBridge (introducing native USDC) –  are already expanding the ecosystem’s capabilities. With this momentum, Zilliqa is emerging as the high-performance Layer 1 where institutions, innovators, and real-world value collide.

If you’re a developer and want to build dApps on Zilliqa 2.0, please refer to the technical documentation.

About Zilliqa:

Zilliqa is a high-performance Layer 1 blockchain platform built to power scalable, secure, and interoperable decentralized applications. As the first public blockchain to implement sharding, Zilliqa has consistently pushed the boundaries of blockchain infrastructure. With the launch of Zilliqa 2.0, the platform is evolving to meet the needs of institutions, enterprises, and developers seeking high-throughput infrastructure with the trust, transparency, and flexibility required for real-world adoption.

To learn more, visit www.zilliqa.com or follow @zilliqa for regular updates.

Press Contact

Shilika Jain

PR Lead (On behalf of Zilliqa)

Dubai, UAE, 30th June 2025, ZEX PR WIRE, LF Labs (LF Coin) gained momentum today despite broader market pressure, drawing attention as Shiba Inu struggles to reclaim key levels. While SHIB battles resistance, LF Labs pushes ahead by building a full-stack Web3 ecosystem with real-world utility. The project’s growing influence and recent developments position LF Coin as a breakout contender in the crypto space.

LF Labs Builds End-to-End Crypto Tools

LF Labs is creating a unified Web3 infrastructure by combining its LF Wallet, PoS devices, and a powerful startup accelerator. The Low Frequency Accelerator fuels early-stage projects with both funding and liquidity, helping them sustain growth in volatile markets. Because of this strong foundation, LF Coin offers more than just a digital asset; it supports practical use cases and long-term value.

LF Coin trades at $0.000567 today, with a 24-hour volume of $750,308, showing strong investor engagement despite a 9.13% decline. However, the recent price dip comes amid a wider market pullback, not a specific project weakness. LF Labs continues to build momentum by offering real-world solutions that reduce fragmentation in the Web3 ecosystem and support seamless user access.

By supporting early-stage startups with both capital and trading infrastructure, LF Labs addresses a critical gap in the blockchain space. Unlike typical venture capital models, its program boosts token stability and market presence. As a result, LF Coin gains strategic importance for both retail users and businesses entering crypto.

Shiba Inu Eyes Recovery After Heavy Drop

Shiba Inu trades at $0.0000107, struggling to hold its footing after losing 25% of its monthly value. This decline followed panic selling triggered by US military actions, leading to broad crypto liquidations. However, SHIB is showing signs of a potential reversal from the $0.0000106 support level.

As the price rebounds for the third time in six months, a double-bottom pattern may be forming. If successful, SHIB could rise 64% to retest the $0.000017 neckline formed during its April rally. The key confirmation would come from a weekly close above that level, backed by rising spot volume.

RSI at 38 shows oversold conditions, suggesting buyers might step in soon. But the 50-day SMA above the price keeps short-term momentum bearish for now. Until SHIB breaks $0.0000168, bulls remain cautious despite historical support patterns.

LF Labs now leads in utility-driven growth, while Shiba Inu seeks technical recovery from long-term support. As short interest spikes on SHIB, a potential short squeeze could support upward momentum. But for now, LF Coin stands out as a more stable and practical crypto opportunity.

In mid-January, industry-leading digital marketing agency Drive Social Media brought its national team together for an inspiring ”Workshop Week”, a multi-day event designed to strengthen cross-market collaboration, innovation, and agency culture. Hosted at the company’s St. Louis headquarters, the gathering united professionals from all six regional offices, reinforcing the agency’s dedication to professional growth and client success.

A National Gathering with Purpose

Spanning from January 9 to 12, Workshop Week functioned as more than a team meeting, it was a strategic rallying point. The aim? Develop unified approaches to client service, cultivate creative excellence, and align staff from Atlanta, Miami, Nashville, Dallas, Tampa, and St. Louis around the agency’s brand promise.

Stephen Nations, Vice President of Digital Marketing, described it as a “Drive family reunion,” highlighting the event as a moment to reflect on the previous year’s milestones while setting new performance targets. This structure fosters unity across markets and reinforces DSM’s shared values and client-oriented mission.

Learning from Industry Champions

A signature feature of Workshop Week was the lineup of world-class guest speakers. Sessions included experts from across sectors, creativity, technology, sports, memory, and talent acquisition:

1. Duncan Wardle, former Disney Creative & Innovation head
2. Reed Low, ex‑NHL player and broadcaster
3. Ron White, memory expert
4. Jared Cohen, Director of Marketing at Miura Golf
5. Andy Goff, ex‑Talent Lead at Google & X
6. Kate DeWulf, founder of The Big Apple Red campaign

These speakers weren’t just motivational, each offered tangible lessons to amplify DSM’s client strategies. From innovation in campaign ideation to audience psychology and creative problem-solving, their insights equipped Drive Social Media’s team to drive deeper value for clients.

Empowering Agency Leadership

Internal leadership also played a central role. Presentations from DSM’s executive team including COO Stephanie Jenkins, CEO Josh Sample, and VP of Project Management Jennifer Hamilton, provided visibility into the agency’s direction, strategic goals, and cultural evolution.

These sessions centered on nurturing a high-performance, client-first culture, reflecting DSM’s mission to treat client success as a shared responsibility. Strategists, analysts, creatives, and project leads all left with greater ownership and purpose.

Team-Building with a Twist

Evenings during Workshop Week were dedicated to fostering relationships across offices through immersive team-building activities. While details were kept under wraps, attendees described the energy as electric, filled with laughter, strategic discussions, and a renewed connection to mission and peers.

This investment in a culture not only strengthens internal bonds but also ensures a seamless, consistent experience for clients working with multiple DSM locations. A unified team translates to a unified service.

Why This Matters for Clients

In an industry driven by creativity and performance, continuity and cohesion across teams directly impact client success. When every office, be it Miami or St. Loui shares the same strategic DNA, marketing efforts are amplified and outcomes are aligned.

Workshop Week allows DSM to:

Real-World Impact

Drive Social Media’s commitment to alignment isn’t just cultural, it’s measurable. Their proprietary Marketing Milk platform collates real-time data from all offices, ensuring consistent metrics across regions. Clients across HVAC, dental, fitness, retail, and home services enjoy unified reporting and strategy, regardless of geography.

Events like Workshop Week enhance this capability by ensuring that every employee understands campaign objectives, performance dashboards, and ROI targets, making every campaign data-backed and goal-driven.

Looking Ahead: Innovation in Action

DSM plans to expand Workshop Week’s impact in future years, integrating:

1. Client co-creation sessions
2. Industry deep-dives for vertical-specific tactics
3. AI-driven analytics roundtables
4. Post-event incubator groups to pilot new campaign approaches

By enabling direct work with specialist teams post-event, DSM ensures learnings transform into innovative client strategies.

In Summary

Drive Social Media’s Workshop Week exemplifies how a growth-focused agency can sharpen its internal culture to better serve clients. Through expert-led learning sessions, strong team cohesion, and clear strategic alignment, DSM enables its staff to outperform consistently.

For businesses seeking a data-driven marketing partner with genuine cross-market collaboration, Drive has made an unmistakable move forward. Their unified, forward-thinking team ensures campaigns are more creative, more measurable, and more effective, no matter where your target audience is located.

About Drive Social Media

 

 

 

 

Founded in 2012 and headquartered in St. Louis, Drive Social Media is a full-service, ROI-driven marketing agency. Combining proprietary analytics, cross-market ideation, and best-in-class creative, Drive serves clients nationwide helping businesses grow smarter with every campaign.

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Why Dogecoin Cloud Mining Matters in 2025

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